Ebola virus recurs in eye of Ebola patient 9 weeks after viremia cleared
Long technical article in New England Journal of Medicine. | The current outbreak of EVD is believed to have begun in December 2013.1 As of April 26, 2015, a total of 26,312 cases of EVD (including 10,899 deaths) had been reported in six countries in West Africa (i.e., Sierra Leone, Liberia, Guinea, Mali, Nigeria, and Senegal), the United States, the United Kingdom, and Spain.2 The outbreak has also resulted in the largest number of EVD survivors in history.
Among survivors of EVD, late complications that include ocular disease can develop during convalescence. However, few systematic studies have been conducted on post-EVD sequelae, so the incidence and clinical manifestations of post-EVD ocular complications are unclear. Here, we report the clinical course of a man in whom severe, acute, unilateral uveitis developed during the convalescent phase of EVD. We also report the detection of viable EBOV in aqueous humor obtained from the inflamed eye 14 weeks after the onset of the initial symptoms of EVD and 9 weeks after the clearance of viremia...It is reassuring that samples of conjunctivae and tears tested negative for EBOV, a finding that supports previous studies suggesting that patients who recover from EVD pose no risk of spreading the infection through casual contact
Posted by: Anguper Hupomosing9418 2015-05-09 |