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Science & Technology
Research on mice links fast food to Alzheimer's
2008-12-02
I suspect this is a case of finding what you expect to find. Alzheimer's commonly appears in people around 70, with an incubation period of 10-15 years where the signs aren't visible. So we should see people who were born in 1938 or prior showing the signs, and people born 1948-1953 incubating, their brains steadily shrinking.

McDonalds opened their first store in 1955. Prior to that we had to make do with the Dairy Queen, Twin Kiss, the Dixie Diner, Hot Dog Frank's, Bill Jones' Diner, and probably thousands of other local or regional dispensers of burgers and dogs, fries and shakes. All of these prepared meals to order, rather than grabbing them out from radiation emitted by infrared lamps at a Frederick Taylor-measured productivity-maximized rate using 2.8 man minutes per customer order.

The regionals also sold a wider variety of foods: Illinois and Iowa and neighboring regions were big on pork cutlets. You could get fried brains in Missouri, though I'm not sure why. Nectar and ambrosia in Texas was referred to as a hamburger basket and an order of fried beans. And all across the south you could buy things that taste like chicken but weren't. All of these were delivered by young women named Madge or Trixie or Millie, sometimes on roller skates.

If you were born in 1938 or prior, the fast food phenom didn't hit until you were 17 if you were at the first McDonald's on opening day, with your DA haircut and your gaspers rolled up in the sleeve of your white tee shirt. You'd expect to find those of us who matured subsequent to fast food as an industry -- McDonald's, Burger King, Jack in the Box, and similar joints -- incubating at a much heavier rate, while those in their 80s would be relatively free of the disease.
Mice fed junk food for nine months showed signs of developing the abnormal brain tangles strongly associated with Alzheimer's disease, a Swedish researcher said on Friday.

The findings, which come from a series of published papers by a researcher at Sweden's Karolinska Institutet, show how a diet rich in fat, sugar and cholesterol could increase the risk of the most common type of dementia.

"On examining the brains of these mice, we found a chemical change not unlike that found in the Alzheimer brain," Susanne Akterin, a researcher at the Karolinska Institutet's Alzheimer's Disease Research Center, who led the study, said in a statement.

"We now suspect that a high intake of fat and cholesterol in combination with genetic factors ... can adversely affect several brain substances, which can be a contributory factor in the development of Alzheimer's."

Alzheimer's disease is incurable and is the most common form of dementia among older people. It affects the regions of the brain involving thought, memory and language.
Posted by:Fred

#11  CNN AM > Pert basically argues that the human brain at birth is a self-contained, self-regulating/limiting pool of CHOLESTEROL, and that the addition of fast food cholester = fats puts the brain's normal cholesterol oper system in overload.

* REDDIT > THE SIX MOST GROSSEST ITEMS ON US FAST FOOD MENUS.
Posted by: JosephMendiola   2008-12-02 21:55  

#10  Bah! That's a buncha crap. I've been eating McDonnies blah blah... What were we talking about? Hey, where am I?
Posted by: Hellfish   2008-12-02 21:24  

#9  Research has shown that being a laboratory rat is often hazardous to your health.
Posted by: Procopius2k   2008-12-02 20:18  

#8  I think a factor is the preservatives used in most American foods. Some fat is impossible to lose, as it is dense and fibrous, and will not yield even to liposuction. The doctors call it human transfat. American remains also fail to decompose as rapidly as others, if disinterred. The very long shelf life of hamburger buns, processed cheese, and all the transfat from french fries is only part of the story, as nearly all our food from the grocery store has preservatives. Even OTC meds have shelf lives of 3-10 years! Even our milk is homogenized by law but other nations often cook using fresh products or are literally homemade. When Native Americans or the Caribbean islanders eat store bought food and fast food, they gain weight and have diabetes and other diseases of obesity they didn't have when eating indigenous diets. Then there is the corn syrup in so many products, like soft drinks and candy. They need a test population such as rural Asians that eat no junk food or even access to store bought products. Also, I've seen what was called Alzheimers with fairly rapid onset in a hunter who ate mostly deer and elk, besides homegrown garden vegetables; it was Kreutzfeld-Jacobs (sp) or a form of Mad Cow Disease found in wild game. This disease is caused by prions, a protein not killed by heat. Cooking or sterilization procedures such as autoclaving surgical instruments will not destroy prions, making a misdiagnosis on a surgical patient a potential means of transmission.
Posted by: Danielle   2008-12-02 18:00  

#7  Yet another reason* to end subsidies for corn-sugar.

*as if you needed a reason.
Posted by: Bright Pebbles   2008-12-02 16:14  

#6  Luckily, I'm not a research mouse, so I'm not worried.

That, and I don't make it a habit of eating at fast food joints....
Posted by: Barbara Skolaut   2008-12-02 14:55  

#5  Why didn't PETA protest the cruelty of forcing genetically altered mice to eat happy meals?

Posted by: mhw   2008-12-02 13:40  

#4  Most people do not have a diet of exclusively cheeseburgers, french fries and Coke. Even those who eat only at McDonalds have the option of a salad, orange juice, and a carton of milk on occasion. This feels like the tests that were used to show that cyclamates are dangerous while saccharine is safe, which infuriated my research biochemist father. Interestingly, as I understand it, Canada took the same research to support banning saccharine and promoting cyclamates.

It would be interesting to see a proper study following three identical groups of mice for at least a year: one group eating exclusively junk food, the second part junk food and part normal mouse kibble, and the third exclusively mouse kibble.
Posted by: trailing wife    2008-12-02 12:55  

#3  I'll call hooey as well. For example, as a rule of thumb, Alzheimer's and Schizophrenia are mutually exclusive.

Those with less education are as a group more likely to develop Alzheimer's, as well.
Posted by: Anonymoose   2008-12-02 09:17  

#2  On the other hand, these researcher's did mention that vast quantities of lutefisk were conducive to a long life, healthy skin and fresh breath. I suspect some bias.
Posted by: ed   2008-12-02 07:30  

#1  Couldn't the intake of ANYTHING, combined with the right 'genetic factors' adversely affect several brain substances? I'm sure Nitrogen will give you Alzheimer's if you have enough genetic disposition to it. This is just another attempt to modify peoples behavior to suit you own values. I don't think academics have any more credibility than journalists do any more.
Posted by: bigjim-ky   2008-12-02 07:20  

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