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| Science & Technology |
| Could HPV Vaccine Treat Skin Cancer? |
| 2018-07-07 |
| [Medpage] A novel treatment for squamous cell carcinoma (SCC) using HPV vaccine could some day prove useful in patients who are poor surgical candidates, have multiple lesions, or who defer surgery, researchers reported. A single case report of an elderly woman with multiple, inoperable cutaneous basaloid SCC, showed that systemic and direct intratumoral injection of 9-valent HPV vaccine resulted in complete regression of all cutaneous malignant tumors, according to Anna J. Nichols, MD, PhD, of the University of Miami Miller School of Medicine in Miami, and colleagues. All tumors resolved 11 months after the first injection of vaccine, they reported in JAMA Dermatology. No systemic adverse effects were reported, they added, and at the patient's last follow-up visit 24 months after the first intratumoral dose of the HPV vaccine, there was no clinical evidence of SCC recurrence. "The marked regression of numerous SCCs after initiation of the intratumoral injections eliminated the need for additional treatment," the authors wrote. "Tumors not directly injected with the vaccine also regressed, possibly by local dispersion of the vaccine or its effects on immune-mediated mechanisms. These findings suggest that the 9-valent HPV vaccine can provide a therapeutic option for inoperable cutaneous SCCs, in addition to its approved use to prevent anogenital HPV infection." The mechanisms for the vaccine's therapeutic efficacy in cutaneous malignant tumors are not yet clear, they acknowledged. Similarly, it is not known whether systemic use of the vaccine played a therapeutic role. |
| Posted by:Besoeker |
| #7 Ahh yes... Metformin.... also known as MetaFartIn.... and for good reason. |
| Posted by: CrazyFool 2018-07-07 14:14 |
| #6 Then there is the widely prescribed, dirt-cheap and extensively researched drug Metformin, used mostly for Type II diabetes. Repeated studies have shown that populations which take this drug for years tend to live longer and have less cancers of all kinds. This is independent of its effect on diabetes. Metformin is often used as a comparison drug when other anti-diabetes drugs are being researched. The unusual "side effect" has turned up repeatedly in these studies. |
| Posted by: Anguper Hupomosing9418 2018-07-07 13:19 |
| #5 I expect GLOBAL WARMING and the anticipated burst of heat wave caused melanoma may change their stand. |
| Posted by: Skidmark 2018-07-07 12:41 |
| #4 The state says no I'm not allowed to. Can you pay a private physician to do it, Bright Pebbles? Or go to America in holiday, and get it done here at a drugstore pharmacy. The national Walgreens chain offers HPV innoculations , among others. |
| Posted by: trailing wife 2018-07-07 12:07 |
| #3 Here's a tip you won't get from the NHS; avoid travel to Amesbury BP. |
| Posted by: Besoeker 2018-07-07 04:54 |
| #2 I'm expecting a "unexpected" drop in lots of cancers from the HPV vaccine, just wish I could get vaccinated with it myself. The state says no I'm not allowed to. Thanks NHS... |
| Posted by: Bright Pebbles 2018-07-07 04:41 |
| #1 Yes! I privately guessed that HPV (and other viruses in stem cells) is responsible for most to all of cancer. HPV likes to infect damaged cells, it's not the damage that causes the cancer. |
| Posted by: Bright Pebbles 2018-07-07 04:39 |