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Science & Technology
Major new drug to treat aggressive prostate cancer
2008-07-22
Scientists are hailing a new drug to treat aggressive prostate cancer as potentially the most significant advance in the field for 70 years.

Abiraterone could potentially treat up to 80% of patients with a deadly form of the disease resistant to currently available chemotherapy, they say.
Posted by:3dc

#6  Well if this is true then FINALLY middle aged men get something.
Posted by: Hellfish   2008-07-22 18:47  

#5  Maybe that's why I have mann-boobs. Too much whole-wheat bread.
Posted by: Deacon Blues   2008-07-22 18:30  

#4  Also known to bodybuilders is that whole wheat bread is loaded with estrogens, high enough in some cases to cause gynomastia in very sensitive guys.
Posted by: bigjim-ky   2008-07-22 12:30  

#3   Anonymoose, bodybuilders have had that problem for years, mostly because they monkey around with their test levels on purpose. Anti-aromatase drugs prevent the breakdown to estrogen and can jump start the test production in the HPTA axis. I wonder if these guys are seriously overthinking prostate cancer treatment?
Posted by: bigjim-ky   2008-07-22 12:27  

#2  well, I'm not giving up my weekly prostate checks

what?
Posted by: Frank G   2008-07-22 11:45  

#1  This is a lot more complex than what they are suggesting in the article.

As males age, they produce somewhat less testosterone, which is the male "master hormone", for which there are receptors all over the body. Males also contain a small and very precise amount of estrogen, and if testosterone is not available for their receptors, they are occupied with estrogen, often with very deleterious health results.

To make matters worse, as part of the aging process, males also produce an enzyme that converts testosterone to estrogen.

Athletes who are in non-regulated-competitive sports can take OTC synthetic enzyme blockers that harmlessly limits the loss of testosterone by conversion, preventing the harmful effects of too much estrogen.

Add to that the increasing amounts of chemically similar to human estrogen, plant estrogen, which is being artificially introduced into our food supply by farmers, who use it to increase plant yields, and there is the potential for serious trouble.

The problems associated with testosterone in older males may in fact be due to the conversion to estrogen, instead of the testosterone itself. By blocking the testosterone, it may prevent its conversion to estrogen, which may be the real culprit.
Posted by: Anonymoose   2008-07-22 10:54  

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