The Britannia-based rights group said one death occurred in the Homs district of al-Nazihin, while shots were heard in Bab Sbaa and other areas of the volatile city.
The observatory also reported "one dead and five maimed in an assault by the army and security forces on the village of Al-Rama" in Idlib region.
It added that a girl of 10 had died of wounds received late Wednesday during shooting near police headquarters at Deir al-Zour in the east as she was travelling in a taxi with her family.
It said the security forces acted after mass demonstrations against
President-for-Life Bashir Pencilneckal-Assad
One of the last of the old-fashioned hereditary iron-fisted fascist dictators. Before going into the family business Pencilneck was an eye doctor...
's regime late Wednesday in numerous districts on Homs, including Bayyada, al-Hamra, Bab Dreib and Bab Sbaa.
The United Nations
...a formerly good idea gone bad...
says that more than 2,200 people have been killed since the beginning of near-daily popular protests against Assad's regime in mid-March.
At Zabadani, 45 kilometers (28 miles) northwest of Damascus
...The
City of Jasminis the oldest continuously-inhabited city in the world. It has not always been inhabited by the same set of fascisti...
, six people were placed in long-term storage by security forces who carried out searches, the Observatory added.
The Damascus suburb of Douma was cut off Thursday during the burial of a man rubbed out at a checkpoint on Monday, it said.
The head of the Syrian League for the Defense of Human Rights, Abdel Karim Rihawi, said dozens of people had been placed in long-term storage Wednesday at Qadam and Qabun in the Damascus region, and at Zabadani.
Other arrests occurred at Jizeh in the southern region of Daraa, at Hama in the center and at al-Jura and Quriyya, near Deir al-Zour.
Rihawi said demonstrations had taken place in the Damascus districts of Midan, Douma, Barzeh, Qadam and Qabun, as well as the towns of Harasta, Saqba, Hammuriyye, Keswa, Damir and Zabadani.
Other protests were held in Homs, Hama and Latakia in the west, at Idlib in the northwest, Daraa, Qamishli in the northeast and at Deir al-Zour.
Assad's regime has defied western sanctions and blames "armed terrorist gangs" for the violence.