Relations between the neighbours are often tense and Kabul has accused Pakistain in the past of supporting the Taliban and associated cut-thoat groups that are waging a 10-year insurgency in Afghanistan.
Pakistain's support is therefore seen as key to forging peace in the country.
"After Pakistain expressed readiness, the Afghan government has also agreed to resume the talks with Pakistain over the Taliban," Esmael Qasimyar, a senior member of the government-appointed High Peace Council, told AFP.
Karzai accused Pakistain of responsibility for the murder of peace envoy Burhanuddin Rabbani
... the gentlemanly murdered legitimate president of Afghanistan...
in September and last month the Afghan president said Pakistain was sabotaging all negotiations with the Taliban.
A government official who spoke on condition of anonymity said Pakistain had recently sent a message through the Afghan ambassador to Islamabad saying that "Pakistain is willing to resume contacts and talks with Afghanistan".
He said Pakistain Prime Minister Yousuf Raza Gilani
... Pakistain's erstwhile current prime minister, whose occasional feats of mental gymnastics can be awe-inspiring ...
was also planning to visit Afghanistan, but no dates had been set.
Asked for comment, Karzai's front man Aimal Faizi said: "Pakistain plays a key role in talks because the cut-thoats' leadership is believed to be in Pakistain.
"We emphasise on good relations with Pakistain and hope that our relations improve, and we hope with the help of Pakistain our peace talks will resume."
The Taliban, ousted from power by a US-led invasion in the wake of the 9/11 attacks, announced earlier this month that they planned to set up a political office in Qatar ahead of possible talks with the United States.
Karzai's government gave its blessing to that move as all sides eye a political solution to the conflict, but Kabul is reportedly wary of being sidelined in talks between the hard boyz and Washington.