Mohammad Ajmal Amir Qasab, the sole surviving gunman from the 2008 Mumbai attacks, has been hanged.But Omar Saeed Sheikh is still alive.
The Pakistani national's plea for mercy to Indian President Pranab Mukherjee was rejected earlier this month.
He was executed in prison in Pune early on Wednesday, the Home Ministry said.
The 60-hour siege of Mumbai began on 26 November 2008. Attacks on the railway station, luxury hotels and a Jewish cultural centre claimed 166 lives. Nine gunmen were also killed.
Qasab and an accomplice carried out the assault on the main railway station, killing 52 people. He was convicted of murder and other crimes in May 2010. The Supreme Court upheld his death sentence in August.