You have commented 339 times on Rantburg.

Your Name
Your e-mail (optional)
Website (optional)
My Original Nic        Pic-a-Nic        Sorry. Comments have been closed on this article.
Bold Italic Underline Strike Bullet Blockquote Small Big Link Squish Foto Photo
Science
Scientists Find Alzheimer's Treatment While Trying To Cure Diabetes
2018-01-03
[NYCBSlocal] Although their goal was to cure diabetes, scientists may have stumbled onto a new medication to help treat the devastating effects of Alzheimer's disease.

According to a press release from researchers at Lancaster University, a new drug being tested for diabetes patients was found to have "significantly reversed memory loss" in test subjects and is now being examined as possible treatment for neurodegenerative disorders.

The medication, known as a triple receptor drug ‐ or "triple agonist" ‐ reportedly works in multiple ways to protect the brain against degeneration and promote growth. Researchers say that a study of mice being given the drug found that the animals had an increased ability to learn and retain memories.

"These very promising outcomes demonstrate the efficacy of these novel multiple receptor drugs that originally were developed to treat type 2 diabetes," Professor Christian Holscher said in the release.

The scientists added that the mice showed a decrease in chronic inflammation and amyloid plaques in the brain, which have been linked to the development of Alzheimer's in people.

"With no new treatments in nearly 15 years, we need to find new ways of tackling Alzheimer's," Dr. Doug Brown of the Alzheimer's Society said. "It's imperative that we explore whether drugs developed to treat other conditions can benefit people with Alzheimer's."

The discovery of the diabetes drug's side-effect is not a complete coincidence to the researchers. The findings, published in the journal Brain Research, point to the link between some of the symptoms of diabetes and their link to Alzheimer's. Insulin desensitisation is not only one of the key effects suffered by diabetes patients, the hormone's lack of production has also reportedly been observed in the brains of people affected by the memory-stealing disorder.
Faster please
Posted by:DarthVader

#6  almost as good as a Subpoena'd Hillary's testimony
Posted by: Frank G   2018-01-03 20:36  

#5  So it gets rid of brain plaque...

Literally 'brain bleach'...

Cool!
Posted by: CrazyFool   2018-01-03 20:29  

#4  Victoza is one of the 3 things they were looking at. Its been researched by itself not only for diabetes, but as an appetite suppression drug, and as of 5 years ago, it was seen in humans to have reduced ro reversed the plaques of Alzheimers. Basically they were doing alzeimers brain studies post-mortem on a group, and found a subset of the deceased who had dramatic reductions in brain plaques and Alzheimers. The only thing they all had in common was that they were part of a clinical trial of Victoza and had used it for several years.

So this is good news. If accurate this may not only prevent it, but might reverse Alzheimers to some extent.
Posted by: Injun Bucket8891   2018-01-03 20:09  

#3  isn't this treatment the premise for the story, "Flowers for Algernon" and then the movie "Charlie"

Charlie was mentally retarded in Flowers for Algernon, functioning at the trainable level. The treatment gave him new abilities rather than restoring what had been lost. That book particularly resonated for me because my mother pioneered training programs for mentally retarded children and adults, and created a sheltered workshop for those capable of being trained to do simple assembly work. So I spent quite a few of my days off from school among them, and was keenly aware of how much they yearned to be smart like everyone else.
Posted by: trailing wife   2018-01-03 12:13  

#2  isn't this treatment the premise for the story, "Flowers for Algernon" and then the movie "Charlie"
Posted by: lord garth   2018-01-03 05:13  

#1  chronic inflammation from anywhere in the body affects the brain.

the brain evolved out of genes for the immune system and genes involved with inflammation in the body are involved with removing memories in the brain. The brain has it's own separate immune system.

Posted by: Bright Pebbles   2018-01-03 04:55  

00:00