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Science & Technology
Will Viagra and Cialis Extend Lifespan?
2018-03-27
[Rogue Health & Fitness] Viagra and Cialis, and a third, lesser known drug, Levitra, are used to treat erectile dysfunction. Use of these drugs is associated with a lower risk of heart attacks, and can be used as therapeutics against other disease. Will Viagra and Cialis extend lifespan?

Erectile dysfunction drugs such as Viagra inhibit an enzyme called phosphodiesterase 5, or PDE5. Phosphodiesterase enzymes have varying subtypes, and are found in all tissues. They catalyze the breakdown of two molecules, cGMP and cAMP, into inactive compounds.

PDE5 is upregulated from 2- to 5-fold in human heart disease. Inhibition of PDE5 with sildenafil (Viagra) protects against ischemia/reperfusion injury, which means it increases cellular antioxidant protection mechanisms.
Posted by:Besoeker

#11  Yes they will because you'll want to catch up on all the times you had to turn it down.
Posted by: AlmostAnonymous5839   2018-03-27 22:35  

#10  30 Sil for $14 at Walmart.
Posted by: Omease Gleack6321   2018-03-27 22:09  

#9  *Groan*
to your room, BrerRabbit :-)
Posted by: Frank G   2018-03-27 19:26  

#8  Man goes in chemist. Asks, does V... work? Clerk sez yep 1 will do it. Then he asks can i get it over the counter? Clerk sez that would probably take 2.
Posted by: BrerRabbit   2018-03-27 16:31  

#7  Nothing worse than limp celery and chicken wings!

Yes there is - someone giving you ranch dressing instead of blue cheese dressing. That is sacrilege!
Posted by: Raj   2018-03-27 16:10  

#6  just became available for generic production.

OTC for under $5.00 a pop.
I'm predicting a rise in pharma-tourism.
Posted by: Skidmark   2018-03-27 12:57  

#5  V* in original form just became available for generic production.
Posted by: Glenmore   2018-03-27 09:59  

#4  I was hoping they would pass new agricultural laws so they could spray it on celery so it would not go limp and chewy a day after purchase at the grocey store! Nothing worse than limp celery and chicken wings!
Posted by: Jack Chaiter7913   2018-03-27 08:16  

#3  Sales must be drooping in decline. Dead member market sector no longer the exclusive target.

But what will it do for hearing, vision, and memory loss ?

Posted by: Besoeker   2018-03-27 07:22  

#2  No, if anything, it may shorten your life.

Just paying for them is enough to give one a heart attack! Insurance for the most part will not pay for it.

They need to lower prices quite a bit.
Posted by: Seeking Cure For Ignorance   2018-03-27 06:50  

#1  Buying V: What you should know
Posted by: Skidmark   2018-03-27 06:00  

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