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-Signs, Portents, and the Weather-
Coronavirus round-up: 12,000 confirmed in Iran, only 125 new yesterday in China, and more
2020-03-03


Germany, France, UK offer Iran 5 mln-euro package for coronavirus

Coronavirus in Washington state: 6 dead, 12 others infected
[KOMONEWS] SEATTLE - Six people have now died from the coronavirus in the Puget Sound area and at least 12 others have been infected, health officials said Monday, as King County's top executive issued an emergency declaration in response to the outbreak.

The newest victims in King County announced Monday include:
- A man in his 70s, a resident of LifeCare who was hospitalized at EvergreenHealth. The man had underlying health conditions and died Sunday.

- A woman in her 70s, a resident of LifeCare, was hospitalized at EvergreenHealth. She had underlying health conditions and died Sunday.

- A woman in her 80s, who was hospitalized at EvergreenHealth and was one of the earlier reported infected and died Sunday.

And a Snohomish County man in his 40s at EvergreenHealth has also died. He had been a previously-announced infection.

Overall, five deaths are King County residents and one death is a Snohomish County resident. Of the 12 other reported, confirmed infections, nine are King County residents and three are from Snohomish County.

Gov. Jay Inslee earlier issued a statewide emergency declaration Saturday after a man in Kirkland died of COVID-19, the first such reported death in the United States.
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Mortality rate for coronavirus patients

[Dhaka Tribune]






Iranian council member close to supreme leader dies from coronavirus
[DAWN] A member of a council that advises Iran's supreme leader died after falling sick from the new coronavirus, state radio reported, becoming the first top official to succumb to the illness that is affecting members of the Islamic Republic's leadership. Expediency Council member Mohammad Mirmohammadi died at a Tehran hospital of the virus, state radio said according to AP. He was 71.




Big Pharma coming through?

First batch of experimental coronavirus vaccine shipped for human trials
From a week ago.
[Ynet] The potential treatment was developed in record-breaking 42 days; The first phase of clinical trials in humans is set to begin in April.

American biotech company Moderna Inc., which announced it has completed development of world's first version of a coronavirus vaccine, has shipped on Monday the first batch of its rapidly developed vaccine to U.S. government researchers, who will launch the first human tests, checking whether the experimental shot could help suppress the epidemic originating in China.

The new vaccine, going by the name mRNA-1273, is an mRNA vaccine against the novel coronavirus encoding for a prefusion stabilized form of the Spike (S) protein. The S protein complex is necessary for membrane fusion and host cell infection and has been the target of vaccines against the coronaviruses responsible for Middle Eastern Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS).

Additionally, Pharmaceutical company GSK announced on Monday it was working in concert with Chinese biotech company Clover Biopharmaceuticals on a coronavirus vaccine. The collaboration will revolve around the development of a potential protein-based vaccine known as COVID-19 S-Trimer, manufactured by the Chengdu-based pharma company.





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Posted by:trailing wife

#2  'You don't want to go to war with a president' top infectious disease expert claims but vows to tell the truth on coronavirus, asserting the outbreak is going to be 'bad' as Donald Trump prepares visit to NIH
Posted by: Skidmark   2020-03-03 11:03  

#1  re the 12,000 tested positive in Iran

I'm presuming that for Iran (and maybe for the US eventually), the number of people infected but showing no symptoms is going to prevent us from knowing the real extent of this disease.

If this is also true for Hubai province, the fatality percentages only apply to people with symptoms. Given Hubai's population of 60 million and the probably spread of the virus in its early stages, a significant percentage, say 5%, of its population actually were infected. If so the actual fatality rate is about the same as the seasonal flu. Of course I've made a number of assumptions here and each of them could be wrong.
Posted by: lord garth   2020-03-03 07:57  

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