Late Friday, the coastguard found 16 bodies, including those of three women and a baby, and rescued 63 people from a boat that overturned and sank near the island of Paros.
According to those rescued, around 80 people had been on the vessel.
Three coasties patrol boats, private vessels, a coasties plane as well as divers searched for more survivors, officials said.
The latest tragedy -- the third since Wednesday -- came amid high smuggler activity not seen in Greek waters in months.
Hours earlier, 11 bodies were recovered from another boat that ran aground on an islet north of the Greek island of Antikythera on Thursday evening.
Ninety people stranded on the islet were rescued, the coastguard said.
And on Wednesday, a dinghy carrying
Thirteen people were rescued, while dozens remain missing, Greek authorities said.
Survivors gave conflicting accounts: Some said there had been 32 people on board, while others put the number around 50, a coasties official told AFP.
The UN refugee agency UNHCR said the Folegandros accident could end up being the worst in the Aegean this year, as unknown number of people still missing.
"This shipwreck is a painful reminder that people continue to embark on perilous voyages in search of safety," said Adriano Silvestri, the UNHCR’s assistant representative in Greece.
Earlier Friday, the coastguard had intercepted another boat with 92 men and boys on board after it ran aground on the coast of the Peloponnese peninsula.
Three suspected smugglers who fled the boat on foot were later arrested.
The UNHCR estimates that more than 2,500 people have died or gone missing at sea as they tried to reach Europa
...the land mass occupying the space between the English Channel and the Urals, also known as Moslem Lebensraum...
from January through November this year.
Nearly one million people, mainly Syrian refugees, arrived in the European Union
...the successor to the Holy Roman Empire, only without the Hapsburgs and the nifty uniforms and the dancing...
in 2015 after crossing the sea to the Greek islands close to
...the occupiers of Greek Asia Minor..."These days, the criminal activity of smugglers, who are indifferent to human life, has intensified, stacking dozens of distressed people, without life jackets, on boats that do not even meet the basic safety standards," Giannis Plakiotakis, Maritime Affairs Minister said late Friday pointing the finger at Turkey, saying Ankara "lets smugglers act unchecked."