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2020-03-30 Home Front: Culture Wars

FDA issues emergency authorization of 2 anti-malaria drugs for coronavirus treatment

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Posted by Iblis 2020-03-30 11:26|| || Front Page|| [8 views ] Top

#1 I thought these drugs were already being used in various places? There ought to be some clinical data at this point to give some indication of their efficacy. There ought to be other data that could give some indication of their positive effects. For example, in approved prescribed uses of the drugs for lupus, rheumatoid arthritis, Sjogren's disease and malaria, how many of these people get COVID-19? If the figure is very low, or nil, then one might be able to assume the drugs are preventive or curative for CV-19 without controlled clinical trials.

Posted by JohnQC 2020-03-30 15:22|| 2020-03-30 15:22|| Front Page Top

#2 It was being used off label (potential liability issues) and under compassionate use exception, which means you had to wait until the patient was at death's door. Now doctors can prescribe it with a positive test for COVID-19 when it's most effective.

French have concluded 2 studies, both showing high safety and efficacy. But studies take time, and it's never enough. People will argue n, p values, need for follow up, etc for years. That's fine, but maybe not the ideal way to respond to a crisis.

Posted by Iblis 2020-03-30 15:50|| 2020-03-30 15:50|| Front Page Top

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