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2021-09-14 Science & Technology
The J&J conundrum
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Posted by g(r)omgoru 2021-09-14 02:02|| || Front Page|| [1 views ]  Top

#1 I have had no issues with the J&J vaccine. I'd be more concerned about mix n match problems. But that's just me.
Posted by M. Murcek 2021-09-14 07:45||   2021-09-14 07:45|| Front Page Top

#2 It's the same antigen end product, MM
Posted by g(r)omgoru 2021-09-14 09:20||   2021-09-14 09:20|| Front Page Top

#3 ...and the same RNA - they just get different ways to get it into the system.
Posted by g(r)omgoru 2021-09-14 09:22||   2021-09-14 09:22|| Front Page Top

#4 I like how incredibly complex interactions that have not even been studied in vivo yet can be dismissed as "no worries." See - Castle Bravo test.
Posted by M. Murcek 2021-09-14 09:26||   2021-09-14 09:26|| Front Page Top

#5 ^Jeez MM, you take booster 6 months after the initial - by that time there isn't even a memory of the original shot left (that's why you need a booster)
Posted by g(r)omgoru 2021-09-14 09:29||   2021-09-14 09:29|| Front Page Top

#6 ^ prove it
Posted by Warthog 2021-09-14 09:53||   2021-09-14 09:53|| Front Page Top

#7 g(R) it is not the same mrna. J&J uses a weakened virus to deliver the antigen. The others use a synthetic uricil which doesn't get cut apart by the normal enzymes that degrade natural mrna.
Posted by rammer 2021-09-14 10:57||   2021-09-14 10:57|| Front Page Top

#8 ^Here you are wart 35 Years of Research Into Coronavirus Infections Show Long-Term Immunity Is Unlikely
Posted by g(r)omgoru 2021-09-14 11:40||   2021-09-14 11:40|| Front Page Top

#9 rammer, rammer, rammer.
J&J has an "artificial" virus containing Covid spike protein's mRNA.
mRNA vaccines do the same thing via lipid vesicle
(with proteins that mediate non-destructive entry of these vesicles into cells).

Now, just think - if it was different RNA, then it would result in different protein = different immune response.

Think of it as delivering the same type of cargo by train or by truck.
Posted by g(r)omgoru 2021-09-14 11:49||   2021-09-14 11:49|| Front Page Top

#10 So grom, having had covid and then 5 months later the J&J vaccine, what is the procedure? Start over with Pfizer series, take Pfizer booster, (is there a J&J booster?), I don't know.
Posted by Glenmore 2021-09-14 14:12||   2021-09-14 14:12|| Front Page Top

#11 no, g(r) the mrna in the vaccines is a synthetic uricil. Your body has a dozen enzymes to degrade mrna in your extracellular spaces. These mrna vaccines deliberately change the uricil to be indestructible in your body. It makes the same protein, but it doesn't degrade like your body would otherwise destroy it.

We have evolved to destroy extracellular mrna. That was for a reason, and highly conserved.

Posted by rammer 2021-09-14 20:28||   2021-09-14 20:28|| Front Page Top

#12 The mrna in the J&J vaccine is natural and would be destroyed in extracellular spaces by your body's enzymes.
Posted by rammer 2021-09-14 20:39||   2021-09-14 20:39|| Front Page Top

#13 g(r)you are, in my opinion, a advocate for the pharmaceuticals. I will remember this.
Posted by rammer 2021-09-14 21:08||   2021-09-14 21:08|| Front Page Top

23:42 Skidmark
23:42 SteveS
23:36 Skidmark
23:34 Skidmark
23:33 Skidmark
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23:31 Skidmark
23:29 Skidmark
22:57 Thing From Snowy Mountain
22:57 JohnQC
22:41 Silentbrick
22:31 The Walking Unvaxed
22:28 The Walking Unvaxed
22:26 The Walking Unvaxed
22:25 Rex Mundi
22:22 The Walking Unvaxed
21:42 Cesare
21:27 SteveS
21:08 rammer
21:00 Tennessee
20:52 Procopius2k
20:49 Frank G
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20:39 rammer









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