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2020-07-15 -Signs, Portents, and the Weather-

Covid-19 vaccine developed by US biotech firm Moderna enters final stage trial

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Posted by Besoeker 2020-07-15 03:49|| || Front Page|| [11126 views ] Top

#1 Incidentally, Instapundit - whose site became a forum for Covid-deniers - has an anti-vaccine post already.

Posted by g(r)omgoru 2020-07-15 10:18|| 2020-07-15 10:18|| Front Page Top

#2 The local Dallas paper gave Fauci's NIH top billing in this development, Moderna was second fiddle.

Posted by Bobby 2020-07-15 10:52|| 2020-07-15 10:52|| Front Page Top

#3 Phase 3 trials - where most candidate drugs fail.

Posted by Iblis 2020-07-15 11:50|| 2020-07-15 11:50|| Front Page Top

#4 You can say what you want about the establishment's response to COVID-19, but anti-vaccine posts? Without having seen the post, I'll still say that's a bit strange to say the least.

Posted by Clem 2020-07-15 11:53|| 2020-07-15 11:53|| Front Page Top

#5 A summary of a posted story at Instapundit. I guess you could call it 'anti-vaccine".

Vaccines are hard to develop, and can be dangerous. This is a vaccine for a disease where 40% (at current estimate, up from 35% before) have no symptoms, and where only about .4% die. It’s also a widespread disease — this isn’t Ebola where you could vaccinate 50,000 people and bring an outbreak to an end. You’d have to vaccinate a billion or more. When you vaccinate huge numbers of people for a disease that isn’t very dangerous, your vaccine has to be very safe to be better than the disease. That doesn’t go well with a rushed development effort.

Posted by Bobby 2020-07-15 12:02|| 2020-07-15 12:02|| Front Page Top

#6 BTW, unless I missed something, where are the thousands of new COVID-19 cases caused by the Trump rally in Tulsa a few weeks ago. I guess I didn't get that memo.

Posted by Clem 2020-07-15 12:06|| 2020-07-15 12:06|| Front Page Top

#7 According to the MSM/Press: "Subhumans aren't affected"?

Posted by Frank G 2020-07-15 12:25|| 2020-07-15 12:25|| Front Page Top

#8 #2 You, usually, don't start with scary stories about a specific vaccine unless there some actual examples - that's why they've all this extensive testing. But the author already sure it'll do more harm then good.

p.s. No vaccine can be more dangerous (at least since they've learned not to use wrong adjuvants) as the actual infection.

Posted by g(r)omgoru 2020-07-15 12:33|| 2020-07-15 12:33|| Front Page Top

#9 Its a unique vaccine because it produces a unique "spike protein" signature, so the immune system can learn to attack the virus without the virus itself being put into the body. The vaccine is RNA based, just like the virus, so it might actually be effective in producing lots of specific antibodies. The phase 3 will be important to make sure it doesnt over-rev the immune system, in addition to making sure it does cause the body to produce antibodies for SARS-CoV-2, and that there are no heretofore unseen adverse effects.

If this works, it will be great for high risk for death populations, like people with multiple comorbidities. Those are the populations that should have been concentrated on from the beginning instead of the whole population.

Posted by Marilyn Tojo7566 2020-07-15 12:54|| 2020-07-15 12:54|| Front Page Top

#10 ^Not Ag specific CD8? Just asking - not starting any arguments.

Posted by g(r)omgoru PB 2020-07-15 13:11|| 2020-07-15 13:11|| Front Page Top

#11 The COVID-19 Panic Shows Us Why Science Needs Skeptics

Posted by Clem 2020-07-15 17:42|| 2020-07-15 17:42|| Front Page Top

#12 where are the thousands of new COVID-19 cases caused by the Trump rally in Tulsa a few weeks ago.
I thought hardly anybody actually showed up?

Posted by Glenmore 2020-07-15 18:27|| 2020-07-15 18:27|| Front Page Top

#13 I keep reading that infection does not necessarily confer immunity. If that's true, can vaccine confer immunity?

Posted by Glenmore 2020-07-15 18:28|| 2020-07-15 18:28|| Front Page Top

#14 "I keep reading that infection does not necessarily confer immunity. If that's true, can vaccine confer immunity?"

That's the trick. If the vaccine provokes too small a response, then it could actually makes things worse if you get the disease (see e.g. Dengue vaccine). If it provokes too much response you could get a cytokine storm. And even if you do make antibodies, no one knows how long they will last.

Posted by Iblis 2020-07-15 18:43|| 2020-07-15 18:43|| Front Page Top

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