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2020-03-31 -Signs, Portents, and the Weather-
Coronaplague Roundup: FDA Says Hydroxychloroquine And Chloroquine Can Be Used To Treat Coronavirus
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Posted by Fred 2020-03-31 00:00|| || Front Page|| [11126 views ]  Top

#1 The U.S. Food and Drug Administration (FDA) has approved the use of two anti-malaria drugs to treat patients infected by the new coronavirus (aka COVID19 or Chinese Plague)

So afraid to do their job that they wait for Trump to tell them what to do.
Posted by gorb 2020-03-31 00:36||   2020-03-31 00:36|| Front Page Top

#2 but HCQ and CQ are not approved as a prophylactic.

Probably we don't have enough of the drug to do that.
Posted by lord garth 2020-03-31 00:54||   2020-03-31 00:54|| Front Page Top

#3 /\ The greatest sin for any bureaucrat is to do anything "Original". By following hallowed procedure the bureaucrat can avoid any risk to their job while actually never having to do anything productive.
Posted by magpie 2020-03-31 00:55||   2020-03-31 00:55|| Front Page Top

#4 And now we'll see if the miracle reports had any truth in them.
Posted by g(r)omgoru 2020-03-31 03:28||   2020-03-31 03:28|| Front Page Top

#5 
Posted by g(r)omgoru 2020-03-31 03:30||   2020-03-31 03:30|| Front Page Top

#6 magpie
The problem for bureaucrats is there's little to none up-side for doing a good job...

P.S. I am not a bureaucrat.
Posted by Bright Pebbles 2020-03-31 04:12||   2020-03-31 04:12|| Front Page Top

#7 I've not seen where Nevada or Michigan governors have lifted the 'arrest orders' for doctors using these drugs yet.

Maybe that news was lost in the haze.
Posted by Mullah Richard 2020-03-31 07:56||   2020-03-31 07:56|| Front Page Top

#8 First person who dies in spite of getting the drug will be "Trump's fault." Class action lawyers looking at nailing Trump for failure of leeches on George Washington's deathbed...
Posted by M. Murcek 2020-03-31 08:16||   2020-03-31 08:16|| Front Page Top

#9 Henry Ford Hospital (Detroit) has issued treatment guidance that includes both HCQ as well as remdesivir
Posted by lord garth 2020-03-31 11:31||   2020-03-31 11:31|| Front Page Top

#10 Assuming chloroquine is even partially effective, it will save thousands of lives, and because the media has tied it to Trump he'll get the credit. Total backfire.
Posted by Iblis 2020-03-31 11:41||   2020-03-31 11:41|| Front Page Top

#11 ^ media/DNC Backfire #47
Posted by Lex 2020-03-31 11:54||   2020-03-31 11:54|| Front Page Top

#12 Tocilizumab, which is marketed as Actemra is now being tested in Italy for Covid19.

It is, like HCQ, already approved to treat rheumatoid arthritis.
Posted by lord garth 2020-03-31 13:26||   2020-03-31 13:26|| Front Page Top

#13 I should have added that Tocilizumad is, I think, more costly than hcq and you would need to take more anti biotic with it than you would with hcq
Posted by lord garth 2020-03-31 13:59||   2020-03-31 13:59|| Front Page Top

#14 Re: bureaucrats, they all realize that if you don't do anything at all, you will never do anything wrong--and therefore can't be criticized in the annual reviews.
Posted by Tom 2020-03-31 14:50||   2020-03-31 14:50|| Front Page Top

#15 A bit of perspective, from the CDC. For the period ending March 21, the U.S. CDC reports -

CDC estimates that so far this season there have been at least 39 million flu illnesses, 400,000 hospitalizations and 24,000 deaths from flu.

That's the regular, old fashioned seasonal flu, kiddies, not the Chinese Plague (AKA COVID-19).
And -

Nationally, the percent of laboratory specimens testing positive for influenza at clinical laboratories continued to decrease while ILI [influenza like illnesses] activity continued to increase. More people are seeking care for respiratory illness due to the ongoing COVID-19 pandemic.

Indicating the usual spring decline of the flu.  However, because of the pandemic, more folks who might have stayed home with the drugstore medications are now calling the doctor, fearing they have COVID-19)
Weekly U.S. Influenza Surveillance Report  [see Key Points]
Posted by Bobby 2020-03-31 16:00||   2020-03-31 16:00|| Front Page Top

#16 Low dose hydroxychloroquine (Plaquenil), in combination with azithromycin (Z-pak) may just be working. 3 sources I have found:

Research virologist in France followed his initial small test with a better documented one and showed similar success with 60 patients, only 1 death, 86yo who was "highly advance" before treatment, all the others have recovered.

https://techstartups.com/2020/03/27/coronavirus-cure-new-results-french-study-shows-combination-hydroxychloroquine-plaquenil-azithromycin-successfully-treated-80-coronavirus-patients-significant-dr/

Also Dr. William Grace Lennox Hospital NYC (100+ cases treated): ‘Thanks to hydroxychloroquine, we have not had a death in our hospital.’

And then there is Dr. Vladimir Zelenko. Amazing if true, but a bit skeptical until data published. He is a board certified MD family medicine long in practice in the Haisidic community. He defines success as “Not to die.” He has directly diagnosed/tested and treated 699 patient, zero patients died, zero patients intubated, and four hospitalizations.

Its hydroxychloroquine, in combination with azithromycin (Z-Pak), an antibiotic to treat secondary infections, and zinc sulfate, over a period of 5 days for routine cases. Cost is about $20. Apparently the doses are low enough to control for prolonged QT risk.

Of course this method doesn't get any researchers glory or grants, doesn't enrich drug companies since these are easily and quickly and cheaply manufactured generic drugs 50+ years old, and since it can be used now, off label, it doesn't reinforce the power of the FDA bureaucrats in DC.
Posted by Marilyn Tojo7566 2020-03-31 17:00||   2020-03-31 17:00|| Front Page Top

#17 Thanks for this, Marilyn. There's hope.
Posted by Lex 2020-03-31 17:22||   2020-03-31 17:22|| Front Page Top

#18 Yes, thanks for your analysis and comments MT.
Posted by Besoeker 2020-03-31 17:28||   2020-03-31 17:28|| Front Page Top

#19 Yes, indeed. It is so hard to find a glimmer of light in Mordor.
Posted by Bobby 2020-03-31 19:00||   2020-03-31 19:00|| Front Page Top

#20 "If you find yourself going through hell, keep going."
- Winnie the Flu Churchill
Posted by Lex 2020-03-31 19:04||   2020-03-31 19:04|| Front Page Top

#21 Lots of good news on all fronts except where idiots are concerned.

First person who dies in spite of getting the drug will be "Trump's fault."

They tried that already, but a) it turned out to be fish tank cleaner, and b) the surviving wife turns out to be a serious Democratic party donor.
Posted by trailing wife 2020-03-31 19:29||   2020-03-31 19:29|| Front Page Top

#22 gov of Michigan who wrote letter threatening docs who use hcq now says it was misunderstood and she now asks the US gov to supply MI with hcq
Posted by lord garth 2020-03-31 19:51||   2020-03-31 19:51|| Front Page Top

#23 Of course, if in 25 years, someone who took hydroxychloroquine for the Wuhan flu and survived comes down with cancer or something, lawyers will be all over them trying to sue.
And blaming Trump, of course.
Posted by Rambler in Virginia 2020-03-31 20:41||   2020-03-31 20:41|| Front Page Top

#24 ^Posted for tomorrow :-)
Posted by Frank G 2020-03-31 20:41||   2020-03-31 20:41|| Front Page Top

#25 For #22
Posted by Frank G 2020-03-31 20:44||   2020-03-31 20:44|| Front Page Top

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