Article

2005-10-14 Southeast Asia

Tamiflu-resistant case of Avian Flu in Vietnam

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Posted by lotp 2005-10-14 15:33|| || Front Page|| [5 views since 2007-05-07] Top

#1 Kawaoka said it's not clear whether the low preventive dose had encouraged the emergence of drug resistance.

Quite likely.

Posted by Bobby 2005-10-14 22:00|| 2005-10-14 22:00|| Front Page Top

#2 www.recombinomics.com has been tracking this for almost a year. It is amazing and somewhat troubling that this has recently been so ostentatiously discovered by Governments and the media.

Posted by RWV 2005-10-14 22:05|| 2005-10-14 22:05|| Front Page Top

#3 The girl, who had been caring for an older brother with the disease, had been receiving low doses of Tamiflu as a preventive measure when the virus was isolated in late February. She later fell ill and was given higher doses. She recovered and left the hospital in March.

Kawaoka said it's not clear whether the low preventive dose had encouraged the emergence of drug resistance.

Seems pretty damned clear to me. Administering antibiotics in less-than-treatment-level doses results in antibiotic-resistant bacteria (like a lot of staph strains and antibiotic-resistant TB), so why not viruses?

This is the maddening thing about dispensing drugs to Third World nations - all the time, money, research, and hard work that went into producing a cure for some dangerous malady can be easily pissed away by a lackadaisical attitude toward treatment.

Posted by Bomb-a-rama 2005-10-14 23:36|| 2005-10-14 23:36|| Front Page Top

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